Giant Cell Angiofibroma Scalp: A Rare Neoplasm

Abstract

ABSTRACT Giant cell angiofibroma (GCA) is a rare benign pathologic entity that shows a predilection for the mesenchymal tissue of the orbit and head and neck region. It is a highly vascular, wellcircumscribed benign soft-tissue neoplasm that may simulate a malignant or aggressive process. GCA usually presents as a painful mass that grows slowly or remains stable in size over many years. The incidence of extraorbital GCA is very rare, with only two cases of GCA of scalp reported in the literature. The GCA is characterized by a patternless spindle cell proliferation containing pseudovascular spaces, floret-like multinucleated giant cells and a richly vascularized stroma showing hyalinization or myxoid change. CD34 immunoreactivity remains an important immunohistochemical finding of potential diagnostic value. Surgical excision is often curative. We report a case of a 42 years old male with the primary complaint of a painful solitary nodule arising on the occipital region of the scalp. Complete tumor removal through surgical resection was achieved, and diagnosis of Giant cell angiofibroma was rendered on the histopathological and immunohistochemical examination. The postoperative period was uneventful. How to cite this article Qadri S, Afroz N, Jain A, Shamim N. Giant Cell Angiofibroma Scalp: A Rare Neoplasm. Int J Head Neck Surg 2015;6(1):10-13.