Abstract
The paper describes a case of thyroid hyalinizing trabecular tumor in a 55-year-old woman. Cytological examination of her fine-needle biopsy specimen showed separately lying tumor cells with intracellular cytoplasmic inclusions. Its cytological study determined the trabeculoalveolar structures formed by tumor cells, the intercellular space exhibited a homogenous eosinophilic matter that yielded a positive Schick's test, laminated calcinates that mimick psammoma bodies. Immunophenotyping of the neoplasm revealed a positive reaction with antibodies to thyroglobulin, a negative reaction to galectin-3 and cytokeratin-19, and membrane Ki-67 expression, which suggests the low malignancy potential.
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