Abstract

The Infectious Diseases Society of America guidelines for treating uncomplicated urinary tract infections (UTIs) recommend that nitrofurantoin be used as first-line therapy for cystitis, except when renal insufficiency is present, and that cephalexin be considered as an acceptable alternative. Trimethoprim-sulfamethoxazole and ciprofloxacin are recommended as second- and third-line options, respectively. For pyelonephritis, intravenous ceftriaxone (1g) is recommended when fluoroquinolone resistance exceeds 10%, and outpatient therapy should …

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