Abstract
The biogenesis of the Golgi complex and the maintenance of its supramolecular organization has become subject to renewed interest recently. Much of this discussion has centred around the question of whether the Golgi arises by cisternal maturation of endoplasmic reticulum (ER)-derived membranes, thereby constantly changing its own identity, or whether all transport along the secretory pathway occurs by the fusion and fission of small carrier vesicles between stable preexisting organelles. Many new insights have been gained lately concerning the mechanism of intra-Golgi transport, but much less is known about an intimately related problem: how is the Golgi complex formed?A new study by Rossanese et al. tries to tackle this problem by looking at it from a new angle1xGolgi structure correlates with transitional endoplasmic reticulum organization in Pichia pastoris and Saccharomyces cerevisiae. Rossanese, O.W. et al. J. Cell Biol. 1999; 145: 69–81Crossref | PubMed | Scopus (217)See all
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