Abstract
Gastrointestinal stromal tumors (GISTs) are soft tissue sarcomas that can occur anywhere in the GI tract. There are roughly 4,000 to 6,000 cases diagnosed in the United States annually. GISTs are often asymptomatic early on and can evade detection, occasionally resulting in malignancy. Due to their insidious growth and location, it is suspected that they are more common than currently reported. It is important to know how difficult it is to identify a GIST and the various methods to treat it in a patient. Our case presents a 62-year-old male with incidental findings of multiple GISTs during workup for kidney stones. The patient was fortunate that these tumors were detected before developing into a greater health concern and this case highlights the insidious nature with which they develop.
Highlights
Mesenchymal tumors are soft tissue tumors affecting connective tissue
Genetic studies may aid in identifying gastrointestinal stromal tumors (GISTs), as all GISTs are positive for KIT and CD34 expression, with platelet-derived growth factor receptor alpha mutation appearing in 50% of all cases
GIST is underestimated in the general population [2], as not every death is autopsied, not every GIST develops symptoms, and not every patient has co-morbid conditions that result in an incidental finding
Summary
Mesenchymal tumors are soft tissue tumors affecting connective tissue. The most common system they affect is the GI tract, usually manifesting as gastrointestinal stromal tumors (GISTs) [1]. Common presentations include anemia, abdominal pain, nausea, vomiting, loss of weight or appetite, or even a palpable mass in the abdomen, and GISTs are commonly incidental findings from other exams Once they are suspected, imaging studies can be performed. The patient developed fever, and a CT with contrast was performed This scan showed incidental findings of masses on the gastric fundus. The patient was sent home to recover, and roughly three weeks after the procedure returned for a kidney/ureter/bladder x-ray, which had no relevant findings Follow up with his primary care provider showed well healing surgical incisions, improved energy and positive affect regarding his own health. The patient is scheduled for a six month follow-up with his surgeon for a CT of the abdomen
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