Gestational hypothyroidism (GHT) in previously euthyroid infertile women

Abstract

Hypothyroidism negatively impacts fertility, early pregnancy and fetal development. Thyroid requirements increase in pregnancy. Recent guidelines have recommended that women with a history of infertility or miscarriage be treated with L-thyroxine (T4) if their TSH ≥ 2.5 μIU/mL before or during pregnancy. This study sought to determine the prevalence of mild hypothyroidism in very early pregnancy in previously euthyroid women.