Gestational diabetes diagnosed in third trimester of pregnancy: an observation at a Hospital of Women and Children in Vietnam

Abstract

Background. Gestational diabetes mellitus (GDM) remains a significant concern within the medical community due to its high risk, as well as its serious side effects on both the mothers and the fetuses. This study aims to assess the prevalence and the risk factors of gestational diabetes mellitus in pregnant women at Da Nang Hospital for Women and Children. Methods. A cross-sectional study was conducted on 706 pregnant women at 2428 weeks of gestation at Da Nang hospital to determine the prevalence of gestational diabetes. Multivariate regression analysis was used to clarify the independent risk factors associated with gestational diabetes. All participants were interviewed and tested for the oral glucose tolerance test (OGTT) to identify the number of gestational diabetes, which was diagnosed according to the American Diabetes Association (ADA) diagnostic criteria in 2014. Results. Gestational diabetes prevalence was 10.2%; categorized by the number of matched diagnostic criteria: 1 criterion: 7.1%; 2 criteria: 2.1%; 3 criteria: 1.0%. There are four independent risk factors for gestational diabetes determined through multivariate regression analysis: maternal age > 30 years (OR = 2.376), a history of gestational diabetes (OR = 12.211), pre-pregnancy BMI ≥ 23 kg/m2 (OR = 10.775), a history of fetal macrosomia > 3800 g (OR = 4.655). The risk of gestational diabetes in the group with risk factors was 6.21 times higher than that in the group with no risk factors. Conclusion. More attention should be paid to the risk factors for gestational diabetes, such as maternal age > 30 years, a history of gestational diabetes, pre-pregnancy BMI ≥ 23 kg/m2, a history of fetal macrosomia > 3800 g in all pregnant women.