Abstract

Abstract Objectives: to describe the occurrence of gestational and congenital syphilis in Guarapuava-PR, according to maternal, neonatal characteristics and outcome of cases. Methods: cross-sectional study, retrospective, held in Guarapuava/PR, with secondary data collected in the laboratory of clinical analyses and information system of Compulsory Notification, collected between October 2015 and August/2016, the variables were described through absolute and relative frequencies. Results: of the 40 newborn (NB) children ofpregnant women with syphilis, 30.0% had congenital syphilis. The variables that were associated with were: gestational quarter of positive examination (p=0.008), number of antenatal consultations (p=0.041), gestational risk stratification (p= 0.041) and treatment of partner (p<0.001). The variables that were associated with the occurrence of congenital syphilis were: risk classification at birth (p=0.004) and examination VDRL in the peripheral blood of the NB (p=0.004). Conclusions: reinforcing prenatal, with the early capture of the pregnant woman by basic care, expansion of the diagnostic coverage and timely and adequate treatment of the pregnant woman and partner, as a prophylactic measure of a possible reinfection.

Highlights

  • The study population consisted of pregnant women with syphilis, residents in the city and selected from examinations Venereal Disease Research Laboratory (VDRL) nontreponemal positive test (Jan the Dec/2014)

  • 62.5% women were classified as havinghigh-risk pregnancy and more than seven prenatal consultations, which initiated in the first quarter (90.0%)

  • It was during this period of gestation that occurred the first VDRL test (77.5%), being that most pregnant women (55.0%) conducted an examination and 67.5% were treated for syphilisdates, as their partners, 52.5 percent were not treated

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Summary

Introduction

Even with clinical evidence and epidemiological data, syphilis remains a public health problem worldwide.[1,2,3,4] Worldwide, 1,360,000 of pregnant women were infected, 80% of these were assisted in prenatal programs, 38% showed some adverse result, as fetal and neonatal mortality, prematurity or low birth weight and congenital infection.[5,6]. The Pan American Health Organization (PAHO) has set the reduction of incidence of congenital syphilis to ≤ 0.5 cases per 1,000 alive until 2015.7 This level has not been achieved.On the contrary, the cases feature and configure itself as an epidemic, with an incidence of 1.3/1,000 live births in the Americas[7] and 6.5/1,000 in Brazil.[8] In the period from 2005 to 2016, were notified in the Notification Aggravation Information System (SINAN) 169,546 cases of syphilis in pregnant women in Brazil.[8]. It is considered that underreporting is still an obstacle for epidemiological surveillance.[2,3] In the State of Paraná, from 1,117 diagnosed pregnant women, 455 cases of congenital syphilis were reported.[9]

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