Abstract
Objective: Describe the clinical and epidemiological characteristics, management and survival. Methods: We describe 9 cases of children with extragonadal germinal tumor, located in the sellar and / or suprasellar area, diagnosed in the National Hospital Edgardo Rebagliati Martins - EsSalud during the period 1999-2017.Objective: Describe the clinical and epidemiological characteristics, management and survival. Methods: We describe 9 cases of children with extragonadal germinal tumor, located in the sellar and / or suprasellar area, diagnosed in the National Hospital Edgardo Rebagliati Martins - EsSalud during the period 1999-2017. Results: The average age of presentation is 8.2 years, predominantly in males (55.6%), the main signs and symptoms are vomiting and headache (100%) followed by diplopia (77.7%). The germinal is the most frequent (77.7%). The survival is 77.7%. Conclusion: Brain germinal tumors are infrequent, are usually located in the sellar area and the etiological diagnosis at the beginning and beginning of a specific chemotherapy and radiotherapy treatment show a better response and avoid a second surgery with high survival. DOI 10.25176/RFMH.v18.n4.1727
Highlights
Objetive: Describe the clinical and epidemiological characteristics, management and survival
La histopatología fue germinoma en 7 (77.7%) y no germinoma en 2, ningún caso tuvo deleción o translocación genética
Consensus on the management of intracranial germ-cell tumours
Summary
GERMINAL TUMORS OF THE CENTRAL NERVOUS SYSTEM: EPIDEMIOLOGICAL CHARACTERISTICS AND SURVIVAL IN CHILDREN EDGARDO REBAGLIATI MARTINS-ESSALUD. Métodos: Se describen 9 casos de niños con tumor germinal extragonadal, localizados en el área selar y/o supraselar, diagnosticados en el Hospital Nacional Edgardo Rebagliati Martins - EsSalud durante el periodo 1999-2017. Resultados: La edad media de presentación es 8.2 años, predominan en el sexo masculino (55.6%), los signos y síntomas principales son vómitos y cefalea (100%) seguidos de diplopía (77.7%). Conclusión: Los tumores germinales cerebrales son infrecuentes, se localizan generalmente en el área selar y el diagnóstico etiológico al debut e inicio de un tratamiento específico de quimioterapia y radioterapia demuestran una mejor respuesta y evitan una segunda cirugía con alta sobrevida. Palabras clave: Cáncer germinal; Selar; Supraselar; Infraselar. Palabras clave: Cáncer germinal; Selar; Supraselar; Infraselar. (fuente: DeCS BIREME)
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