German Human Genome-Phenome Archive in an International Context: Toward a Federated Infrastructure for Managing and Analyzing Genomics and Health Data

Abstract

With increasing numbers of human omics data, there is an urgent need for adequate resources for data sharing while also standardizing and harmonizing data processing. As part of the National Research Data Infrastructure (NFDI), the German Human Genome-Phenome Archive (GHGA) strives to connect the data from German researchers and their institutions to the international landscape of genome research. To achieve this, GHGA partners up with international activities such as the federated European Genome-Phenome Archive (EGA) [1] and the recently funded European Genomic Data Infrastructure (GDI) project to enable participation in international studies while ensuring at the same time the proper protection of the sensitive patient data included in GHGA.