Abstract
Cancer is a disease of aging; peak incidence and mortality rates are observed in adults 65 years or older in most cancer types [1]. Due to the aging population worldwide, a sharp increase in the number of older adults is expected during the next decades, e.g., the number of adults aged ≥75 years with cancer is projected being increased with approximately 80% (from 130,000 to 234,000) in the United Kingdom by 2035 [2]. Aging is a highly heterogenous process resulting in increased vulnerability due to the decreased functional reserve capacity of multiple organs [3].
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