Geriatric nutritional risk index is a predictor of recurrent percutaneous coronary intervention in patients with non-ST segment elevation myocardial infarction.

Mehmet Kaplan,Gizem Ilgın Kaplan,Nurbanu Bursa,Mehmet Murat Sucu,Sıma Annac,Fethi Yavuz,Mert Deniz Savcılıoglu,Irfan Veysel Duzen,Gökhan Altunbas,Ertan Vuruskan

doi:10.18087/cardio.2021.8.n1669

Abstract

Aim To investigate the relationship between malnutrition and follow-up cardiovascular (CV) events in non-ST-segment elevation myocardial infarction (NSTEMI).Material and methods A retrospective study was performed on 298 patients with NSTEMI. The baseline geriatric nutritionalrisk index (GNRI) was calculated at the first visit. The patients were divided into three groups accordingto the GNRI: >98, no-risk; 92 to ≤98, low risk; 82 to <92, moderate to high (MTH) risk. The studyendpoint was a composite of follow-up CV events, including all-cause mortality, non-valvular atrialfibrillation (NVAF), hospitalizations, and need for repeat percutaneous coronary intervention (PCI).Results Follow-up data showed that MTH risk group had significantly higher incidence of repeat PCI and all-cause mortality compared to other groups (p<0.001). However, follow-up hospitalizations and NVAFwere similar between groups (p>0.05). The mean GNRI was 84.6 in patients needing repeat PCI and99.8 in patients who did not require repeat PCI (p<0.001). Kaplan Meier survival analysis showed thatpatients with MTH risk had significantly poorer survival (p<0.001). According to multivariate Coxregression analysis, theMTH risk group (hazard ratio=5.372) was associated with increased mortality.Conclusion GNRI value may have a potential role for the prediction of repeat PCI in patients with NSTEMI.

Highlights

The global, elderly population (>65 yrs) has gradually increased over the past few decades
The patients were divided into three groups according to the geriatric nutritional risk index (GNRI): >98, no-risk; 92 to ≤98, low risk; 82 to
The study endpoint was a composite of follow-up CV events, including all-cause mortality, non-valvular atrial fibrillation (NVAF), hospitalizations, and need for repeat percutaneous coronary intervention (PCI)

Summary

Introduction

The global, elderly population (>65 yrs) has gradually increased over the past few decades. The geriatric nutritional risk index (GNRI), which is calculated using both plasma albumin and body mass index (BMI), is a tool for evaluating nutritionrelated risk [3]. This simple and practical assessment tool might be useful for predicting CV events in HF patients [4]. Malnutrition is an independent risk factor for mortality, with several reports showing that GNRI correlated with malnutrition and mortality in patients with CV disease, requiring hemodialysis, or with peripheral arterial disease (PAD) [5,6,7]. These results indicate that GNRI may be a powerful predictor for clinical outcome in various diseases, so it might potentially be used widely in clinical practice

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Discussion

Conclusion