老年GERD患者的临床特征及诊治进展

Abstract

目的：分析老年胃食管反流病(gast roesophageal reflux disease, GERD)患者临床症状特征，并观察疗效。方法：随机选取2011-01/2012-01我院消化内科、老年科门诊及住院部病房符合GERD诊断的患者1000例，将患者分为2组，老年组500例(≥60岁)和非老年组500例(<60岁)。比较2组患者各种症状的发生率以及综合治疗前后RDQ量表评分变化。结果：GERD患者老年组食道外症状的发生率明显高于非老年组(P < 0.01)，综合治疗后与治疗前比较RDQ量表评分均数明显下降(老年组：7.53 ± 3.31 vs 15.63 ± 3.54，P < 0.01；非老年组：6.22 ± 4.52 vs 16.54 ± 5.61，P < 0.01)，2组综合治疗均有明显疗效。结论：老年GERD患者应注意鉴别诊断及多系统综合治疗，才能达到全面康复的疗效。 Aim: To analyze the clinical symptoms of aged patients with gastroesophageal reflux disease (GERD) and to observe the curative effect of comprehensive treatment for GERD. Methods: One thousand out-patients who met the criteria for GERD in our hospital from January 2011 to January 2012 were randomly chosen and allocated to two groups: aged patient group (≥60, n = 500) and non-aged patient group (<60, n = 500). Incidence rate of each symptom was analyzed and compared between two groups. RDQ scores of patients before and after the treatment were estimated. Results: The rates of extra esophageal symptoms in aged group were markedly higher than those in non-aged group (P < 0.01); RDQ scores of GERD patients reduced significantly after comprehensive treatment (aged group: 7.53 ± 3.31 vs 15.63 ± 3.54, P < 0.01; non-aged group: 6.22 ± 4.52 vs. 16.54 ± 5.61, P < 0.01). Remarkable curative effect was observed in both groups. Conclusion: For aged GERD patients, more importance should be attached to differential diagnosis and comprehensive treatment for a complete recovery.