Abstract
Stationary digital breast tomosynthesis (sDBT) with distributed X-ray sources based on carbon nanotube (CNT) field emission cathodes has been recently proposed as an approach that can prevent motion blur produced by traditional DBT systems. In this paper, we simulate a geometric calibration method based on a proposed multi-source CNT X-ray sDBT system. This method is a projection matrix-based approach with seven geometric parameters, all of which can be obtained from only one projection datum of the phantom. To our knowledge, this study reports the first application of this approach in a CNT-based multi-beam X-ray sDBT system. The simulation results showed that the extracted geometric parameters from the calculated projection matrix are extremely close to the input values and that the proposed method is effective and reliable for a square sDBT system. In addition, a traditional cone-beam computed tomography (CT) system was also simulated, and the uncalibrated and calibrated geometric parameters were used in image reconstruction based on the filtered back-projection (FBP) method. The results indicated that the images reconstructed with calibrated geometric parameters have fewer artifacts and are closer to the reference image. All the simulation tests showed that this geometric calibration method is optimized for sDBT systems but can also be applied to other application-specific CT imaging systems.
Highlights
Traditional digital breast tomosynthesis (DBT) systems have been widely used, as such systems can overcome the overlapping phenomenon associated with mammography and can allow for differentiation between normal and pathological tissues on standard 2D projections in clinical settings[1,2,3]
We developed a geometric calibration method based on a projection matrix approach for a square Stationary digital breast tomosynthesis (sDBT) system and verified its performance
The errors of the input geometric parameters and the extracted parameters are compared based on the results of the geometric parameters extracted from the sDBT system
Summary
Traditional digital breast tomosynthesis (DBT) systems have been widely used, as such systems can overcome the overlapping phenomenon associated with mammography and can allow for differentiation between normal and pathological tissues on standard 2D projections in clinical settings[1,2,3]. Geometric calibration of a stationary DBT system based on distributed CNT X-ray source arrays (JCYJ20160608153434110, JCYJ20150831154213680), the Applied Science and Technology Project of Guangdong Province in China (2015B020233014), the Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province (2014B030301013)
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