Abstract
Geographical and temporal weighted regression (GTWR) model is a local regression linear model, which indirectly reflects the spatio-temporal non-stationary characteristics of the study data by calculating the trends for changes in parameters with space and time. Recently, GTWR model has become one of the hot topics in the study on spatio-temporal heterogeneity of diseases. This review summarizes the basic principles and study methods of the GTWR model, and describes the applications of this model in epidemiology.
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