Abstract

Serious bleeding is the most feared adverse effect of vitamin K antagonists (VKA) such as warfarin. VKA-treated patients who are bleeding (or found to have a supratherapeutic INR value) can be managed by administering one or more of the following: vitamin K, fresh frozen plasma, recombinant activated factor VII, or prothrombin complex concentrates. Current guidelines and review articles addressing this subject are discordant. We tested the hypothesis that significant clinical practice differences exist between North America and the rest of the world for reversal of VKA-associated coagulopathy.

Highlights

  • The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality

  • The goal from this study is to evaluate weaning predictor indexes in patients during weaning from mechanical ventilation (MV)

  • This study aims to evaluate the effects of the threshold in such situations

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Summary

Introduction

The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality. Methods A total of 48 community patients (36 men, 11 women, age 50.17 ± 17.974 years, APACHE II score 13.51 ± 6.153) who were expected to stay in the ICU for >5 days were included in this study. Specific examples of feedback are as follows: ‘good update of management plan reinforces need for taking into account concurrent medication when resuscitating patients’, ‘nice simple messages with good starting points for trying to deal with these complicated patients’, ‘useful data on risk of recurrence as this is a question often asked by patients’ This feedback was encouraging as it showed how the primary care professionals planned to change their practice to improve patient outcomes as a result of the learning. The course was considered excellent by 63% of the participants and good by 36%

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