Abstract
Geographic Altitude and COVID-19: Parameters for a better recognition of severe disease
Highlights
Authors Samuel Pecho-Silva Universidad Cienti ca del Sur, Lima, Peru; Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru. https://orcid.org/0000-0002-7477-9841
Some authors postulate that living at a higher geographic altitude, especially above 2,500 meters above sea level, provides some protection against SARS-CoV-2 infection due, among other factors, to higher production of angiotensinconverting enzyme and lower number of receptors for this enzyme, greater tolerance to Hypoxemia, a higher level of hemoglobin, greater presence of ultraviolet radiation that would inactivate the virus, lower temperature and lower humidity, adaptive processes to inflammation caused by lower barometric pressure, greater relative physical activity, greater exposure to ultraviolet rays and greater synthesis of vitamin D, among others; all these aspects are no more than unconfirmed hypotheses[4,5]
Another argument in favor of the supposed protection of geographical altitude and lower barometric pressure revolves around the fact that a lower prevalence of COVID-19 has been reported at a higher level of geographical altitude
Summary
Authors Samuel Pecho-Silva Universidad Cienti ca del Sur, Lima, Peru; Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru. https://orcid.org/0000-0002-7477-9841. Rodriguez-Morales Universidad Cienti ca del Sur, Lima, Peru; Latin American Network of COVID-19
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