Abstract
The genus Viburnum (Adoxaceae, Dipsacales) is of scientific interest due to the chemical components and diverse biological activities found across species of the genus, which includes more than 230 species of evergreen, semievergreen, or deciduous shrubs and small trees. Although frequently used as an ornament, the Viburnum species show biological properties with health-promoting effects. Fruits, flowers, and barks of certain species are used for pharmaceutical purposes or as cooking ingredients, hence containing biochemical compounds with health-promoting activity such are carotenoids, polyphenols, and flavonoids. However, its taxonomical determination is difficult, due to its wide distribution and frequent hybridizations; therefore, an objective classification would allow us to understand its biological activity based on its phytochemical components. More than sixty phytochemical compounds have been reported, where vibsanin-type diterpenes and their derivatives are the most prevalent. Leaves and twigs of V. dilatatum contain the largest number of phytochemicals among the genus. Through preclinical evidence, this study provides insight regarding antioxidant, antibacterial, anti-inflammatory, cytotoxic, and anticancer activities of genus Viburnum.
Highlights
The genus Viburnum (Adoxaceae, Dipsacales) is comprised of more than 230 species of evergreen, semievergreen, or deciduous shrubs and small trees distributed primarily within the temperate forest regions of the northern hemisphere and in the mountains of Central and South America, Southeast Asia (Philippines, Malaysia), and southeastern Australia and Tasmania. the species of the genus are generally well adapted to mesic forest environments, particular species have been reported to inhabit both, cold boreal forests, and tropical rainforests, as is the case of Viburnum edule and Viburnum amplificatum, respectively
The genus Viburnum (Adoxaceae, Dipsacales) is of scientific interest due to the chemical components and diverse biological activities found across species of the genus, which includes more than 230 species of evergreen, semievergreen, or deciduous shrubs and small trees
Flowers, and barks of certain species are used for pharmaceutical purposes or as cooking ingredients, containing biochemical compounds with health-promoting activity such are carotenoids, polyphenols, and flavonoids
Summary
The genus Viburnum (Adoxaceae, Dipsacales) is comprised of more than 230 species of evergreen, semievergreen, or deciduous shrubs and small trees distributed primarily within the temperate forest regions of the northern hemisphere and in the mountains of Central and South America, Southeast Asia (Philippines, Malaysia), and southeastern Australia and Tasmania. Flowers, and barks of certain species are used for pharmaceutical purposes or as cooking ingredients, containing biochemical compounds with health-promoting activity such are carotenoids, polyphenols, and flavonoids. These biochemical components are responsible for the main biological activities of Viburnum plants, and the antioxidant, antibacterial, antiinflammatory, and cytotoxic activity have been well documented, some current research links to the chemical components found in Viburnum exerting protection and treatment against diseases. Studies undertaken to assess within-species variability in terms of bioactive compounds profile and content [32,33,34] facilitate breeding and subsequent growing of viburnums as pharmaceutical crops
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