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Abstract
GenPop is a web based online cross platform tool developed to help Geneticist and Epidemiologist to deal with association studies in analyzing human population genetic data. The tool features include descriptive analysis such as Hardy-Weinberg equilibrium test, chi-square p-value and analysis of single nucleotide polymorphisms (SNPs) with multiple inheritance models such as dominant, recessive, allelic, genotype, odd's ratio and relative risk at 95% confidence interval and analysis of multiple SNPs including haplotype frequencies and linkage disequilibrium for a pair of biallelic markers. This is a user-driven human population genetic data analysis tool that is easily scalable and acceptable with multiple implementations of different algorithms. GenPop has been developed using PHP, JavaScript and with PHPExcel library to analyse the genetic data for case control studies.
Highlights
Genetic epidemiology deals with the study the role of genetic factors involved in determining health and diseases in families and as well in populations which seeks to derive statistical and quantitative analysis of how genetics work in larger groups
There are various software packages developed for analyzing human genetic data which rely on computer-based algorithm that is not passable in certain instances, few packages provide a single
Thereby as a constraint of trend in the use of worldwide Web technology and Web design that aims at enhancing creativity, information sharing and communication among users in analysing the case control data
Summary
Genetic epidemiology deals with the study the role of genetic factors involved in determining health and diseases in families and as well in populations which seeks to derive statistical and quantitative analysis of how genetics work in larger groups. There are various software packages developed for analyzing human genetic data which rely on computer-based algorithm that is not passable in certain instances, few packages provide a single Statistical packages can be used to perform these study analysis, but an assistance of computational tool is mainly needed by researcher to perform specific analysis like HWE, haplotype estimation, and at times difficulty in integrating results from different packages at a shorter time span [1].
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