Abstract
Genotypic Patterns of Secreted Aspartyl Proteinase Gene in Various Candida Species Isolated from Antenatal Women with Vulvovaginal Candidiasis
Highlights
In recent years there is an increased frequency of Candida infection and it has been the cause of a major rise in morbidity and mortality[1]
There is a predominance of the SAP1 gene in Candida isolates from asymptomatic women whereas SAP1 and SAP9 genes in Candida isolates from symptomatic women
The statistical analysis showed a significant difference for the SAP7 and SAP8 gene frequency among the Candida isolated from symptomatic and asymptomatic women
Summary
In recent years there is an increased frequency of Candida infection and it has been the cause of a major rise in morbidity and mortality[1]. The usual presentations are persistent curdy white vaginal discharge with itching, bad odour, irritation, pain in the lower abdomen and induration of vulva This infection is an unpleasant, intolerant condition for women[2]. Sap enzyme production is related to various other virulence factors of Candida species including, hyphal development, adhesion to the surface, phenotypic exchanging, and dimorphism[12]. Being thereof 10 SAP genes, during their sequential activation in particular phases of infection, they organize as well as constitute a robust body and indicate that distinct members of this gene family having a significant role in the adaptive response of Candida species to its environment, including its host[13]. The point of this investigation was to assess the genotypic patterns of SAP (SAP1 to SAP10) genes in Candida causing VVC in antenatal women
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
