Abstract
Objectives/Aims:Bitewing and digital dental panoramic radiographs have become important adjuvants for successful dental practice in pediatric dentistry. Both methods lead to genetic changes in the oral buccal epithelium that have not yet been satisfactorily explored. The aim of the present study was to evaluate the genotoxic effects induced by X-ray radiation from bitewing and panoramic dental radiography in exfoliated buccal epithelial cells of children, using the Buccal Micronucleus Cytome assay.Materials and Methods:Children (n=40) who met the inclusion criteria and provided signed informed consent were included in the study. Children were selected for undergoing bitewing radiographs (group 1; n=20) or digital dental panoramic radiographs (group 2; n=20). Exfoliated buccal mucosal cells were obtained by scraping the right/left buccal mucosa with a wooden spatula immediately before the X-ray exposure and 10±2 days after exposure.Results:The frequency of micronuclei increases significantly post exposure to both bitewing and digital dental panoramic radiography in children, but the frequency was higher in bitewing radiographs.Conclusion:It was concluded that the frequency of micronuclei increases post exposure to both bitewing and digital panoramic radiographs. Increased radiation exposure results in an increase in micronuclei frequency.
Highlights
Roentgenography is an important diagnostic method with wide application in pediatric practice
P values o0.05 were considered statistically significant. From this ex vivo study conducted to evaluate the extent of genetic changes on the basis of MN frequency in exfoliated buccal mucosa cells before and after exposure to bitewing and panoramic radiographs, the following conclusions were drawn: Age
An increase in MN frequency in exfoliated cells was observed as a result of radiotherapy. This was in relation to other studies,[12,13,14,15,16] but to our knowledge this is the first study to evaluate the MN frequency from bitewing radiographs in children aged 6–9 years and from digital dental panoramic radiographs in children aged 10–12 years
Summary
Roentgenography is an important diagnostic method with wide application in pediatric practice. The panoramic radiograph, known as rotational panoramic imaging, an extra oral radiographic technique that images both the maxilla and the mandible on single exposure, is used. This is mostly indicated for the assessment of growth and development of jaws of children and adolescents, to view the mixed dentition stages, and the status and stages of resorption of primary dentition. In both radiographic methods, the oral buccal epithelium is directly exposed to ionizing X-ray radiation.[2]
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