Abstract
Genomics of emerging infectious disease: A PLoS collection.
Highlights
There is no simple definition of an emerging disease, but it can be loosely described as a disease that is novel in some way—for example, one that displays a change in geographic location, genetics, or function
Emerging infectious diseases are caused by a wide range of organisms, but they are perhaps best typified by zoonotic viral diseases that cross from animal to human hosts and can have a devastating impact on human health, causing a high disease burden and mortality [8]
Despite the fact that sequencing is the method of choice for characterizing new disease agents, and new substantially faster and cheaper sequencing methods are continually being produced, we still lack the range of computational tools necessary to analyze these sequences in sufficient detail [4]
Summary
There is no simple definition of an emerging disease, but it can be loosely described as a disease that is novel in some way—for example, one that displays a change in geographic location, genetics, or function. Gupta et al [1] provide Google.org’s perspective and vision for how systematic application of genomics, proteomics, and bioinformatics to infectious diseases could predict and prevent the pandemic. You will find the views of leading researchers from several different disciplines, and a provocative vision from a funding agency, and the contributions of six different PLoS journals (PLoS Biology, PLoS Medicine, PLoS Computational Biology, PLoS Genetics, PLoS Neglected Tropical Diseases, and PLoS Pathogens).
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