Abstract
Genome-wide association studies getting more complicated but help is on the way
Highlights
Human geneticists have been expecting that, with the availability of a dense set of genetic markers across the genome and high-throughput genotyping technologies, genome-wide association studies will be feasible and will lead to the discovery of major genetic factors contributing to susceptibility to common human diseases
Several million single nucleotide polymorphisms (SNPs) have been genotyped by the International HapMap Consortium and the resultant HapMaps have been used to develop sets of markers that can be typed on high-throughput genotyping platforms at reasonable cost
Human geneticists are already coming up with strategies to address these problems, and the papers found in this issue of Human Genomics are representative of this movement
Summary
Genome-wide association studies getting more complicated but help is on the way Human geneticists have been expecting that, with the availability of a dense set of genetic markers across the genome and high-throughput genotyping technologies, genome-wide association studies will be feasible and will lead to the discovery of major genetic factors contributing to susceptibility to common human diseases.
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