Abstract

Colonization of the nasal mucosal with Staphylococcus aureus and the production of superantigenic enterotoxins by the bacteria are crucial amplifying factors of the pro-inflammatory mechanisms operating in chronic upper airways diseases such as chronic rhinosinusitis and nasal polyposis.

Highlights

  • Colonization of the nasal mucosal with Staphylococcus aureus and the production of superantigenic enterotoxins by the bacteria are crucial amplifying factors of the pro-inflammatory mechanisms operating in chronic upper airways diseases such as chronic rhinosinusitis and nasal polyposis

  • We demonstrated that S. aureus enterotoxin B may influence important pathways linked to T-cell receptor, interferon signalling and adaptative immune response

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Summary

Open Access

Claudina Perez Novo1*, Camilla Rydberg Millrud, Natalie De Ruyck, Gabriele Holtappels, Koen Van Crombruggen, Lars Olaf Cardell, Claus Bachert. From The 10th Symposium of Experimental Rhinology and Immunology of the Nose (SERIN 2015) Stockholm, Sweden. From The 10th Symposium of Experimental Rhinology and Immunology of the Nose (SERIN 2015) Stockholm, Sweden. 19-21 February 2015

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