Abstract
The complete genomes of foot-and-mouth disease (FMD) viruses recovered in Libya and Saudi Arabia in 2013 are described here. These viruses belong to an FMD virus lineage (Ind-2001, topotype Middle East-South Asia, serotype O) which is normally endemic in the Indian subcontinent. A contemporary virus sequence from Bhutan is also reported here.
Highlights
The complete genomes of foot-and-mouth disease (FMD) viruses recovered in Libya and Saudi Arabia in 2013 are described here
During November 2013, the FAO World Reference Laboratory for FMD (WRLFMD, Pirbright, United Kingdom) received Foot-and-mouth disease virus (FMDV) isolates causing outbreaks in Libya (LIB) and Saudi Arabia (SAU). Phylogenetic analysis of their VP1 coding sequences revealed that these viruses belonged to the Ind-2001 lineage within the Middle East-South Asia (ME-SA) topotype of serotype O (O/ME-SA/Ind-2001), together with contemporary viruses from Bhutan (BHU) and India. These findings were unexpected, since other contemporary FMD viruses from LIB and SAU grouped within the PanAsia-2 lineage, or within the East Africa 3 (O/EA-3) topotype in Libya
The O/ME-SA/Ind-2001 lineage was initially identified in the Indian subcontinent in 2001 as a group distinct from the predominant PanAsia lineage (WRLFMD) [1]
Summary
The complete genomes of foot-and-mouth disease (FMD) viruses recovered in Libya and Saudi Arabia in 2013 are described here. FMDV is classified in seven serotypes and multiple genotypes, topotypes, and lineages, from which new FMD viruses can emerge to challenge diagnostic tools and vaccination control programs. During November 2013, the FAO World Reference Laboratory for FMD (WRLFMD, Pirbright, United Kingdom) received FMDV isolates causing outbreaks in Libya (LIB) and Saudi Arabia (SAU).
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