Abstract
The genome of a virus isolated from an outbreak of foot-and-mouth disease (FMD) in Morocco in 2015 is described here. This virus is classified as lineage Ind-2001d within serotype O, topotype ME-SA (Middle East-South Asia). This lineage is endemic on the Indian subcontinent but has caused outbreaks in the Middle East and North Africa since 2013.
Highlights
The genome of a virus isolated from an outbreak of foot-and-mouth disease (FMD) in Morocco in 2015 is described here
Phylogenetic analysis revealed relationships of the Moroccan isolates to other viruses in the Middle EastSouth Asia (ME-SA) topotype, Ind-2001d lineage (O/ME-SA/ Ind-2001d) [3]. Viruses belonging to this FMD virus (FMDV) lineage were originally isolated in the Indian subcontinent, but their emergence in the Middle East (United Arab Emirates and Saudi Arabia) and North Africa (Libya) was reported in 2013 [4, 5], with further spread to Algeria and Tunisia in 2014 [6, 7]
The genome sequence of O/MOR/1/2015 was 8,115 nucleotides in length [including 15 nt of a poly(C) tract of unknown length located within the 5= untranslated region (UTR)]
Summary
The genome of a virus isolated from an outbreak of foot-and-mouth disease (FMD) in Morocco in 2015 is described here. The virus is classified into seven immunologically distinct serotypes, each containing numerous variants that are often restricted to specific geographical locations (topotypes) and lineages [1]; due to a high mutation rate, new FMD viruses can emerge and challenge local and international disease control strategies. FMD virus (FMDV) serotype O was confirmed to be the causative agent.
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