Abstract

ABSTRACTWe report here the sequence of a genotype 2a reference strain of hepatitis E virus (HEV), developed on behalf of the World Health Organization. The HEV reference strain is intended for use in assays based on nucleic acid amplification for the validation of HEV RNA detection.

Highlights

  • We report here the sequence of a genotype 2a reference strain of hepatitis E virus (HEV), developed on behalf of the World Health Organization

  • The IRP is intended for standardization of nucleic acid tests, similar to panels developed for other bloodborne viruses [11]

  • The genotype 2a strain (Mex-14) in the World Health Organization (WHO) IPR was obtained from a patient in Telixtec, Mexico, in August 1986

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Summary

Introduction

We report here the sequence of a genotype 2a reference strain of hepatitis E virus (HEV), developed on behalf of the World Health Organization. The 1st World Health Organization (WHO) International Reference Panel 8578/13) for HEV [10] contains strains representative of one to four HEV genotypes, including genotype 2a.

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