Genome sequence and comparative analysis of DRQ-2, the type strain of Nonomuraea indica

Abstract

Strain DRQ-2T (type strain of Nonomuraea indica) is worthy for genome sequencing, due to its ability to produce a wide variety of industrially important enzymes such as amylase, asparaginase, cellulase, gelatinase, glutaminase, and protease. Genome sequencing and comparison of strain DRQ-2T is described in the present work. The genome size was estimated to be 8,288,417 (bp) that consisted of 59 contigs. The G + C content of the genome was 72.4%. A total of 7730 genes were predicted with two rRNAs and 64 tRNAs. The genome analysis of the strain DRQ-2T showed the presence of a wide range of secondary metabolite gene clusters. Pan-Genomes Analysis Pipeline (PGAP) indicated that strain DRQ-2T had large numbers of unique genes. The majority of N. indica DRQ-2T genes encode for hypothetical proteins, indicating the functions of these ortholog clusters were still remain to be determined.