Abstract

To determine whether the norovirus strain GII.17 recently detected in Maryland, USA, (Hu/GII.17/Gaithersburg/2014/US) is spreading globally, we characterized the genome. High similarity with the norovirus GII.17 that caused recent outbreaks in Asia indicates that the same strain was present in the United States during the 2014–15 norovirus season (winter).

Highlights

  • To determine whether the norovirus strain GII.17 recently detected in Maryland, USA, (Hu/GII.17/Gaithersburg/2014/ US) is spreading globally, we characterized the genome

  • Because noroviruses are prone to recombine within the ORF1/ORF2 junction, strains with different combinations of P and G genotypes can be detected in nature [7]

  • A fecal sample was collected from the child and tested for norovirus by reverse transcription PCR (RT-PCR) by using generic primers that annealed to the polymerase region

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Summary

Introduction

To determine whether the norovirus strain GII.17 recently detected in Maryland, USA, (Hu/GII.17/Gaithersburg/2014/ US) is spreading globally, we characterized the genome. Several norovirus strains circulate, for ≈2 decades, GII.4 has been the predominant genotype infecting humans. Increased detection of GII.17 as the predominant outbreak strain in China has been reported [9].

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