Abstract
Evidence is presented to support the hypothesis that the increase in the cellular DNA content in Anacystis nidulans, which occurs in association with an increase in growth rate, indicates an increase in the number of genomes in the cell. The extent of killing and mutant reversion effected by the mutagen nitrosoguanidine was far greater in a slow-growing culture than in a fast-growing one. And, when DNA synthesis was inhibited by mitomycin C, the number of division cycles taking place before growth ceased was larger in fast-growing cultures than in slow-growing ones.
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