Abstract
Genome Medicine: stem cells, genomics and translational research
Highlights
Welcome to a new series of articles on stem cell genomics to be published in this and upcoming issues of Genome Medicine. ese contributions sample just a few of the many exciting developments in the field of stem cells and genomic research and project ahead to future advances that will make a clear imprint on medicine
Embryonic stem (ES) cells can produce the entire repertoire of cells of the body, a property called pluripotency
Bone marrow transplantation (BMT), a life-saving procedure for which the Nobel Prize was awarded to E Donnall omas in 1990, has been used for more than three decades to treat aplastic anemia and leukemia [1]
Summary
Welcome to a new series of articles on stem cell genomics to be published in this and upcoming issues of Genome Medicine. ese contributions sample just a few of the many exciting developments in the field of stem cells and genomic research and project ahead to future advances that will make a clear imprint on medicine. Stem cells are defined by two properties: self-renewal, the generation of more identical cells, and developmental potency, the capacity to give rise to more differentiated cells. Blood-forming (hematopoietic) stem cells (HSCs), which sustain blood formation through our entire lives, are restricted in their developmental potential to generate only blood cell lineages.
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