Abstract
Human mpox is a re-emerging orthopox virus infection. We report a 36-year-old Nigerian male who presented with a one-week history of insidious onset ulcer at the base of the penis with no associated extra-genital rash or constitutional symptoms. He had unprotected heterosexual intercourse 14 days prior to the onset of the genital lesion, with a partner who had itchy vagina discharge. Physical examination revealed a solitary granulating ulcer measuring 3 cm by 2.5 cm with multiple satellite pustular lesions. No extra-genital lesion was observed. Polymerase chain reaction of the swab of lesions was positive for mpox. This was atypical mpox which should be considered by clinicians evaluating persons for sexually transmitted diseases.
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