Abstract
Crohn's disease is an inflammatory bowel disease that can have multiple extraintestinal manifestations and can develop prior to, following, or simultaneously with gastrointestinal tract involvement (Aberumand et al. (2017), Georgious et al. (2006), Larsen et al. (2010), Levine and Burakoff (2011), Louis et al. (2018)). This report examines the case of a 16-year-old male with a rash of the genital, intergluteal, and inguinal regions refractory to antimicrobial treatments suspicious for an extraintestinal manifestation of Crohn's disease. The patient was diagnosed with inflammatory, nonfistulizing colonic Crohn's disease following presentation with gastrointestinal symptoms including abdominal pain and bloody stools 6 months after the onset of the rash. The genital lesions resolved after starting treatment for Crohn's disease with adalimumab.
Highlights
Crohn’s disease (CD) is a type of inflammatory bowel disease that can present with extraintestinal manifestations and can develop prior to, following, or simultaneously with gastrointestinal tract involvement and symptoms [1,2,3,4,5]. ese extraintestinal manifestations may present as cutaneous lesions of the genital region
CD is a multisystemic chronic inflammatory disorder that can present with cutaneous findings preceding gastrointestinal symptoms of CD such as abdominal pain and bloody stools
Recognition of extraintestinal cutaneous manifestations of CD can lead to a timely diagnosis and treatment of CD with resolution of both intestinal and extraintestinal symptoms. us, when encountering genital or intertriginous rashes refractory to antimicrobial treatments, underlying inflammatory bowel disease should be investigated (Figure 3)
Summary
Crohn’s disease (CD) is a type of inflammatory bowel disease that can present with extraintestinal manifestations and can develop prior to, following, or simultaneously with gastrointestinal tract involvement and symptoms [1,2,3,4,5]. ese extraintestinal manifestations may present as cutaneous lesions of the genital region. Crohn’s disease (CD) is a type of inflammatory bowel disease that can present with extraintestinal manifestations and can develop prior to, following, or simultaneously with gastrointestinal tract involvement and symptoms [1,2,3,4,5]. Ese extraintestinal manifestations may present as cutaneous lesions of the genital region. Extraintestinal manifestations of Crohn’s disease can manifest as cutaneous noncaseating granulomas outside of the gastrointestinal tract and is referred to as metastatic Crohn’s disease [1, 5–9]. Cutaneous manifestations of CD may occasionally precede intestinal involvement and can occur anywhere on the body including the genital regions [2–7]. Anti-TNF medications have been used in the management of Crohn’s disease with improvement of extraintestinal manifestations of Crohn’s [7, 10]
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