Genistein binding protein targets in dental pathogens.

B Vivek Babu,

doi:10.6026/973206300171109

Abstract

Oral pathogens have created a menace in recent years due to biofilm formation and antimicrobial drug resistance. The current treatment strategy works well with antibiotics. However, constant use of antibiotics creates a selective pressure, which increases adaptability of the pathogens. Therefore, it is of interest to analyze the potential targets of genistein in dental pathogens using computer aided prediction tools.

Highlights

Antimicrobial agents have long been used to target pathogenic microorganisms
The growth inhibition of S. aureus that is mediated by inhibition of subcellular location of virulence proteins was in the cytoplasm, topoisomerase IV [21]
Data shown here is consistent with the with an exception of serine/threonine protein kinase and sensor above report where genistein was found to act on a common histidine kinase/response regulator, which were found in the target DNA topoisomerase IV A and B

Summary

Introduction

Antimicrobial agents have long been used to target pathogenic microorganisms. In many instances the antibiotics administered found to exhibit antioxidant, antimicrobial, anti-inflammatory and anticancer properties. It is of interest to analyze the potential targets of genistein in dental pathogens using computer aided prediction tools. It is of interest to analyze the potential targets of genistein in dental pathogens using compter aided prediction tools.

Results

Conclusion