Genetics of Frontotemporal Dementia

F.W Rohlfing,R.K Tu

doi:10.3174/ajnr.a4972

Abstract

FTD : frontotemporal dementia In 1892, Arnold Pick, a neuropsychiatrist at the University of Prague, made the first description of frontotemporal dementia (FTD). In his case report, “On the relationship between senile atrophy of the brain and aphasia,” he described a 71-year-old man who

Highlights

In 1892, Arnold Pick, a neuropsychiatrist at the University of Prague, made the first description of frontotemporal dementia (FTD)
FTD is considered a presenile dementia, 20%–25% of patients with FTD are older than 65 years
WHAT ARE THE CLINICAL MANIFESTATIONS OF FRONTOTEMPORAL DEMENTIA? FTD has 3 main clinical manifestation groups based on dominant symptoms at diagnosis

Summary

Introduction

In 1892, Arnold Pick, a neuropsychiatrist at the University of Prague, made the first description of frontotemporal dementia (FTD). FTD has 3 main clinical manifestation groups based on dominant symptoms at diagnosis. 10 Rohlfing Jan 2017 www.ajnr.org ioral variant, which may represent 70% of FTD.[5] Frontal variant FTD results in alterations in interpersonal skills and behavior. Progressive nonfluent aphasia variant is another manifestation group where patients present with word-finding difficulty.

Results

Conclusion