Abstract

To determine the extent to which mutations in genes known to cause familial hemiplegic migraine (FHM) account for the disorder, the authors used a population-based approach through the Danish National Patient Register. In members of 42 families with FHM, they sequenced the exon and promoter regions of the CACNA1A and ATP1A2 genes. They also sought the Q1489K mutation in the SCN1A gene. Mutations …

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