Abstract
Arabidopsis is universally resistant as a species to many crop pathogens, including examples from other crucifers such<br />as Albugo candida and Hyaloperonospora parasitica from Brassica oleracea. This species level trait could potentially<br />provide a source of durable disease resistance in crops if examples can be found which are amenable to molecular genetic<br />characterization. Our research has developed from the observation that null mutation in Arabidopsis of a defense regulatory<br />gene EDS1 (enhanced disease susceptibility) is susceptible to isolates of A. candida and H. parasitica from brassica.<br />EDS1 is required by a major structural class of R-genes to confer resistance in Arabidopsis. We have therefore focused<br />on identifying R-genes in Arabidopsis that are responsible for conferring resistance to brassica pathogens.
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