Abstract

In this review, we comprehensively discuss recent reports of heritability and genetic associations using candidate gene and genome-wide association (GWA) approaches in circadian and sleep phenotypes in adults, including chronotype (morningness-eveningness), sleep duration and daytime sleepiness, circadian rhythm sleep-wake disorders, and insomnia. Recent findings derive from GWA studies with objective measures and candidate gene studies examining the role of genetic ancestry and health disparities for sleep and circadian measures. The discovery of key, novel genetic markers using various methods has critical implications for future research in terms of identification, treatment, and countermeasures in the field of sleep medicine.

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