Abstract
Huntington disease (HD) is a neurodegenerative disease that afflicts about 1 in 10,000 individuals. Symptoms include uncontrollable choreiform or dance-like movements, impairment in memory and reasoning ability, and alterations in personality. The average age of onset of symptoms is about 40 years. The symptoms become increasingly disabling with time, and patients die 15 to 20 years after the first signs appear. Children constitute approximately 10% of HD cases. They are more severely affected than adults and suffer more rigidity in movement.
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