Abstract

Genetics of Man, by F. Clarke Fraser and James J. Nora, ed 2; 352 pp, with illus, $31, Philadelphia, Lea & Febiger, 1986. Thompson and Thompson's Genetics in Medicine has established itself as a useful text for medical students and physicians having no prior knowledge of genetics. The purpose is introduce medical students to the principles, language and methods of human genetics and to indicate some of its actual and potential medical significance. This edition, the first revised solely by Margaret W. Thompson, continues a successful tradition. The format remains that of previous editions. Initially, chapters are devoted to reviewing principles of medical genetics: cytogenetics and the clinical spectrum of chromosomal aberrations; single-gene inheritance, illustrated by hemoglobinopathies and metabolic disorders; molecular genetics; and multifactorial inheritance. A series of topics is then succinctly covered as separate chapters: immunogenetics, blood grouping, somatic-cell genetics, population genetics, twins, developmental genetics, linkage and mapping,

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