Abstract
This review aims to sketch a current scenario of colorectal cancer (CRC). Findings say that males are the most susceptible to CRC than the females. BRAF and RAS mutations are known as common causes of CRC. Not only targeted therapy but also a combination of radio- and chemotherapy is very useful in CRC.
Highlights
Colorectal cancer (CRC) is known as colon, rectal or bowel cancer
This review aims to sketch a current scenario of colorectal cancer (CRC)
BRAF and RAS mutations are known as common causes of CRC
Summary
Colorectal cancer (CRC) is known as colon, rectal or bowel cancer. CRC is the third most common cancer worldwide (WHO 2015). In this context, males (44.8%) are more susceptible than females (34.1%). Major risks associated with CRC are familial adenomatous polyposis, hereditary nonpolyposis, inflammatory bowel disorder (e.g.Crohn's disease and ulcerative colitis), polyps (any types), rectal bleeding/iron anemia deficiency anemia or with known genetic mutations. Some other risk factors include diet (e.g.- red and processed meat, alcohol), obesity, smoking, lack of physical activity (NCI 2014; World Cancer Report 2014; ). To be noted that vaginal metastases from CRC may be linked with vaginal bleeding or sensation of a vaginal swelling. Aim of this review is to note down current circumstances on CRC
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