Genetically Predicted Lipid Traits, Diabetes Liability, and Carotid Intima-Media Thickness in African Ancestry Individuals: A Mendelian Randomization Study.

Abstract

HomeCirculation: Genomic and Precision MedicineVol. 15, No. 6Genetically Predicted Lipid Traits, Diabetes Liability, and Carotid Intima-Media Thickness in African Ancestry Individuals: A Mendelian Randomization Study No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextGenetically Predicted Lipid Traits, Diabetes Liability, and Carotid Intima-Media Thickness in African Ancestry Individuals: A Mendelian Randomization Study Opeyemi Soremekun, PhD, Eric A.W. Slob, PhD, Stephen Burgess, PhD, Palwende Romuald Boua, PhD, Segun Fatumo, PhD and Dipender Gill, BMBCh, PhD Opeyemi SoremekunOpeyemi Soremekun The African Computational Genomics (TACG) Research Group, Entebbe, Uganda (O.S., S.F.). *O. Soremekun and E.A.W. Slob contributed equally. Search for more papers by this author , Eric A.W. SlobEric A.W. Slob https://orcid.org/0000-0002-1644-0735 Medical Rsrch Council Biostatistics Unit, University of Cambridge, UK (E.A.W.S., S.B.). Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands (E.A.W.S.). Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam, the Netherlands (E.A.W.S.). *O. Soremekun and E.A.W. Slob contributed equally. Search for more papers by this author , Stephen BurgessStephen Burgess https://orcid.org/0000-0001-5365-8760 Medical Rsrch Council Biostatistics Unit, University of Cambridge, UK (E.A.W.S., S.B.). Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, UK (S.B.). Search for more papers by this author , Palwende Romuald BouaPalwende Romuald Boua https://orcid.org/0000-0001-8325-2665 Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé, Centre national de la Recherche scientifique et technologique (CNRST), Nanoro, Burkina Faso (P.R.B.). Sydney Brenner Institute for Molecular Bioscience, Johannesburg, South Africa (P.R.B.). Division of Human Genetics, National Health Laboratory Service and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (P.R.B.). Search for more papers by this author , Segun FatumoSegun Fatumo https://orcid.org/0000-0003-4525-3362 The African Computational Genomics (TACG) Research Group, Entebbe, Uganda (O.S., S.F.). MRC/UVRI & LSHTM, Entebbe, Uganda (S.F.). London School of Hygiene and Tropical Medicine, London, UK (S.F.). H3Africa Bioinformatics Network (H3ABioNet) Node, Center for Genomics Research and Innovation, NABDA/FMST, Abuja, Nigeria (S.F.). †S. Fatumo & D. Gill contributed equally as last authors. Search for more papers by this author and Dipender GillDipender Gill Correspondence to: Dr Dipender Gill, Department of Epidemiology and Biostatistics, School of Public Health Imperial College London, Praed St, London, W2 1NY, UK, Email E-mail Address: [email protected] https://orcid.org/0000-0001-7312-7078 Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK (D.G.). Chief Scientific Advisor Office, Research and Early Development, Novo Nordisk, Copenhagen, Denmark (D.G.). †S. Fatumo & D. Gill contributed equally as last authors. Search for more papers by this author Originally published10 Nov 2022https://doi.org/10.1161/CIRCGEN.122.003910Circulation: Genomic and Precision Medicine. 2022;15Footnotes*O. Soremekun and E.A.W. Slob contributed equally.†S. Fatumo & D. Gill contributed equally as last authors.For Sources of Funding and Disclosures, see page 610.Correspondence to: Dr Dipender Gill, Department of Epidemiology and Biostatistics, School of Public Health Imperial College London, Praed St, London, W2 1NY, UK, Email Dipender.[email protected]ac.ukDr Segun Fatumo, London School of Hygiene and Tropical Medicine, Department of Non-communicable, Disease Epidemiology, Keppel St, London, WC1E 7HT, UK, Email segun.[email protected]ac.uk