Abstract

By adding a genetic “barcode” to the genome of relatively harmless Bacillus thuringiensis subsp kurstaki (Btk), this bacterial species can be used much more effectively to simulate how Bacillus anthracis—a far more dangerous pathogen, whose spores might be used again by terrorists—disperses in various environments, according to Henry S. Gibbons of the Edgewood Chemical Biological Center at Aberdeen Proving Ground in Aberdeen, Md., and his collaborators. Without that special coding, it is virtually impossible to distinguish Btk spores that are deliberately released in simulatory experiments from those that are naturally occurring, they point out. Their findings appeared online September 21, 2012 in Applied and Environmental Microbiology (78:8601–8610).

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