Genetical analysis of mastitis and reproductive traits in first-parity Holstein cows using standard and structural equation modelling

Abstract

The present study aimed to investigate the causal relationships between clinical mastitis and some reproductive traits, including success at first insemination (SFI), the number of inseminations to pregnancy (INS), the interval from calving to first service (CTFS), first and last service interval (IFL), and open days (OD) in first-parity Holstein cows. For this purpose, the records of 58 281 first parity Holstein cows were analysed. These data sets were collected from 17 large dairy herds from 2008 to 2017. Recursive Mixed Models (RMMs) were applied and compared with the estimations under Standard Mixed Models. Then, one trivariate and three bivariate Gaussian-threshold models were used for the analyses. Recursive models were applied, considering that clinical mastitis can influence fertility traits. Mastitis is considered a covariate for the reproductive traits to determine their causal relationship. The results of this study indicated that causal effects of mastitis on SFI (on the observed scale, %), CTFS, IFL, OD, and INS were −5.7%, 3.3 days, 12.27 days, seven days, and 0.26 services, respectively. The estimated structural coefficients of the recursive models in the first parity imply that mastitis significantly lengthened the fertility interval and decreased the conception rate. In addition, genetic, residual, and phenotypic correlations between mastitis and the reproductive traits under both models were statistically significant. Results of genetic correlations between mastitis and fertility traits suggest that more incidence of mastitis during lactation is related to the delays in the heat show and pregnancy rate after insemination. In summary, considering the causal effects under RMMs may be advantageous to comprehend complicated relationships between complex traits better.