Abstract
Breast cancer is the most frequently diagnosed cancer in women and ranks second among causes for cancer-related deaths in women. The heritable component in familial clustering of breast cancer has been estimated to be 73% and the environmental proportion 27%. These high penetrance traits and the identification of the breast cancer-predisposing gene PTEN, warrant further research. In this analysis, we specifically looked at PTEN single nucleotide polymorphisms (SNPs) and their association with breast cancer.
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