Abstract

Experiments were conducted with two different drug-resistant strains of Trypanosoma cruzi that, after mixing, were fed to uninfected triatomid bugs and allowed to develop in the gut of the invertebrate host. In no instance was it possible, upon reisolation of flagellates from fecal matter of triatoma in culture, to demonstrate T. cruzi resistant to both drugs. The failure to achieve cross transfer of drug-resistance by trypanosomes developing in the insect gut, is taken as added evidence against syngamy in trypanosomes.

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