Abstract
The goals of this study were to isolate and to estimate the genetic susceptibility to retinopathy of prematurity. A retrospective study from three centers was performed with zygosity data for premature twins who were born at a gestational age of < or = 32 weeks and survived beyond a postmenstrual age of 36 weeks. Retinopathy of prematurity was diagnosed and staged by pediatric ophthalmologists at each center. Data analyses were performed with mixed-effects logistic regression analysis and latent variable probit modeling.
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