Abstract

Memorable positive and negative experiences produce different profiles of gene expression in brain areas associated with long-term memory.

Highlights

  • T ry to recall your earliest memory

  • Immediate-early gene activation is used as a marker of when and where synaptic plasticity is taking place (Flavell and Greenberg, 2008; Minatohara et al, 2015)

  • The analysis focused on five brain areas which react to memorable events and play a crucial role in long-term memory (Catani et al, 2013)

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Summary

Introduction

T ry to recall your earliest memory. Chances are this experience took place a few decades ago. A memory is created when a significant signal is received from the environment and activates groups of neurons in the brain. Immediate-early gene activation is used as a marker of when and where synaptic plasticity is taking place (Flavell and Greenberg, 2008; Minatohara et al, 2015).

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