Abstract
This commentary refers to our published article, as highlighted in this article most common gene causing breast cancer in the population living in the United Arab Emirates is BRCA2 followed by BRCA1 [1]. This is the first publication discussing about clinical and pathological features of breast cancer in woman with a positive genetic mutation in the United Arab Emirates
Highlights
Received date: May 18, 2021, Accepted date: June 07, 2021. This commentary refers to our published article, as highlighted in this article most common gene causing breast cancer in the population living in the United Arab Emirates is BRCA2 followed by BRCA1 [1]
In the neighbouring countries of the UAE, the Gulf Cooperation Council (GCC), mutations were found mainly in BRCA1/2 genes and in more than 30 non-BRCA1/2 genes associated with breast cancer [6]
In the Kingdom of Saudi Arabia (KSA), breast cancer was diagnosed at an early onset possible due to predisposing genetic factors due to high rates of consanguineous marriage [7]
Summary
This commentary refers to our published article, as highlighted in this article most common gene causing breast cancer in the population living in the United Arab Emirates is BRCA2 followed by BRCA1 [1]. This is the first publication discussing about clinical and pathological features of breast cancer in woman with a positive genetic mutation in the United Arab Emirates. Breast cancer (BC) is the most common cancer in the UAE according to GLOBOCAN statistics in 2020 [2]. In the UAE, most common genetic mutations involving breast cancer were BRCA1 and BRCA2 in patients from Middle East and Asian ethnic background [5].
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