Abstract
A case–control study was performed to assess the potential influence of CYP19 Arg264Cys and CYP1B1 Leu432Val polymorphisms on breast cancer risk in a series of Korean breast cancer patients and controls. The results suggest that the CYP19 Arg264Cys polymorphism modifies breast cancer risk (OR=1.5, 95% CI=1.1–2.2), especially in association with alcohol consumption (P for interaction=0.04), whereas the CYP1B1 Leu432Val polymorphism appears to play no role here.
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